Gotu Kola

Ekrem

Yönetici-Admin
Yönetici
Süper Mod
Üyemiz
Mesajlar
9,119
Gotu Kola bitkisi, Gotu Kola bitkisi kullanımı, Gotu Kola faydaları, Gotu Kola varis.

Gotu Kola, maydanozgiller familyasındandır. Kırmızımsı-beyaz gövdeli, tırmanıcı, ya da gölgeli çayırların sığ sularında dalgalanan, çok yıllık, otsu bir bitkidir. Uzunca bir sapın taşıdığı böbreksi yapraklan vardır. Haziran-eylül aylarında yaprakların oltuklarından çıkan kırmızı-yeşii, beyaz ya da solgun pembe çiçekleri ancak dikkatli bakıldığında görülür. Küçük meyveler olgunlaşınca ikiye ayrılır. Çin’de ve Hindistan’da 2 bin yıldır bilinir. Tropikal bölgelerde, özellikle Madagaskar, Hindistan ve Çinhindi’nde bulunur.
Etken maddesi asyatik ve madekasik adlı triterpenik saponinlerdir. Ayrıca magnezyum, kalsiyum, sodyum, tanenler, şekerler, serbest amino asitler ve K vitamini bulunur. Yara iyileştirici, iltihap giderici, özellikle de egzamayı köreltici, böcek sokmalarını etkisizleştirici etkilerinin yanında, idrar artırıcı, mide ülserini iyileştirici ve zihinsel rahatsızlıklarda hipnoz edici etkileri vardır.

Son araştırmalarda sakinleştirici ve depresyon giderici etkilerinden söz edilmektedir. Bitki asıl, “beynin besini” olarak adlandırılır. Hatta espriyle onun aracılığıyla bir “fil hafızasına sahip olunacağı” söylenir. Bir Sri Lanka atasözü şöyle der: “Günde iki yaprak alırsan yaşlılığı yanına yaklaştırmazsın.” Damar tıkanıklıklarında (varis ağrılarında) yararı kanıtlanmıştır. Yüksek tansiyona katkısı kanıtlanma aşamasındadır.

Ağızdan klasik kullanımı kaygıyı gidermeye, hafızayı ve bilişsel kapasiteyi artırmaya yöneliktir Dışardan yaralara, kesiklere, yanıklara, cerrahi operasyonlara, iltihaplara karşı uygulanır. Kapsül ya da komprime olarak günde iki-üç defada 60 mg alınır.

Çay olarak 150 mi kaynar su, 2-4 gram bitkinin üzerine dökülür, 5-10 dakika sonra süzülerek içime hazır hale gelir. Günde üç bardağa kadar içilir.
Ünlü ilaç şirketi Roche’un, “Lokal deri ülserleri, meme başı çatlak ve yaraları, küçük cerrahi müdahaleler, perine yırtılmaları, epizyotomiler, sünnet sonrasında, yüzeysel yanıklarda endikedir” açıklamasıyla eczanelerde 40 gramlık alüminyum tüpte satışa sunduğu “Madecassol” merheminin bileşiminde bolca gotu kola bulunur. Ekstre yapraklardan ve saptan elde edilir.
Ayrıca bugün ülkemizde, bitkiden yapılan hazır ekstreler bulunmakta olup, bunlardan yemeklerle birlikte günde iki kapsül alınır.

Not: hamilelerle emzikli kadınlar kullanmamalıdır!
 

Ekrem

Yönetici-Admin
Yönetici
Süper Mod
Üyemiz
Mesajlar
9,119
Gotu Kola (Centella asiatica [Latin]),Afrika,Asya,Avustralya,Hindistan ve Güney Amerika gibi tropikal ve yarı tropikal bölgelerde yetişen bir bitkidir.Ayurvedik tıpta 1000 lerce yıldır,hafızayı kuvvetlendirmek ve sinir sisteminin sağlığı için kullanılıyor.Son klinik çalışmalar bu geleneği doğruluyor.

Gotu kola beyne oksijen sağlayan damarları koruyor.Klinik çalışmalar gotu kolanın konsantrasyonu artırdığını gösteriyor.Yapılan çalışmada gotu kolanın test skorlarında artışa neden olduğu gözlenmiş.

Gotu kola anksiyeteye yatkın ve depresyon hastası insanlarda da rahatlatıcı etkiye sahip.

Ayurvedik tıp gotu kolayı deri iltihaplanması ve cüzzam gibi deri hastalıklarının tedavisinde de öneriyor.Yapılan araştırmalar gotu kolanın cüzzama karşı etkili olduğunu doğruluyor.

Gotu kola iltihap kurutucu etkisinin yanı sıra damarları ve kılcal damarları kuvvetlendirerek ,hasarlı dokulara daha fazla kan akışını sağladığından daha çabuk iyileşmelerine yardım ediyor.

Gotu kola asiatikozit isimli bir aktif madde içerir ,bu madde cüzzama neden olan bakterinin koruyucu çeperini parçalar,böylece bağışıklık sisteminin bakteriyi yok etmesini sağlar.

Çalışmalar gotu kolanın diğer cilt problemleri için de etkili bir tedavi olabileceğini gösteriyor.

Bir çalışmada , skleroderma(deri sertleşmesi)hastalığından muzdarip hastalara haftada 3 kere 20 mg gotu kola ekstresi verilmesi neticesinde,deri ve eklemlerin daha esnek olduğu gözlenmiştir.

Gotu kola selülite karşı ,glikosaminoglkan maddesinin üretimini artırarak etkili olur.

Glikosaminoglkanlar bacaklardaki damarları çevreleyen bağ dokuların güçlendirilmesi için de gereklidir.

Çalışmalar gotu kolanın bacak ağrısı ve şişlerinde ,varis tedavisinde etkili olduğunu gösteriyor.

Gotu kola yüksek tansiyonu düşürür.Gotu kolanın merhemi kollagen üretimini düzenler ve yaraların iyileşmesine yardım eder.

Gotu kola sedef hastalığına iyi gelir.

Gotu kala hamile ve emziren bayanlarca kullanılma-malı.Sakinleştirici kullanalarda narkotik etkiye neden olabilir ,tansiyon düşrücü ilaç kullananlarda ilaların etkilerini artırabileceğinden kullanılmamalı.

Bazı insanlarda cilt tahrişineneden olabilir ayrıca merhem formunun aşırı kullanılması cilt kanserine neden olabilir.
 

Ekrem

Yönetici-Admin
Yönetici
Süper Mod
Üyemiz
Mesajlar
9,119


Overview:

Gotu kola (Centella asiatica) has been used to treat a number of conditions for thousands of years in India, China, and Indonesia. It was used to heal wounds, improve mental clarity, and treat skin conditions such as leprosy and psoriasis. Some people use it to treat respiratory infections such as colds, and it was used for that in the past in China. It has been called "the fountain of life" because legend has it that an ancient Chinese herbalist lived for more than 200 years as a result of taking gotu kola.

Historically, gotu kola has also been used to treat syphilis, hepatitis, stomach ulcers, mental fatigue, epilepsy, diarrhea, fever, and asthma. Today, in the U.S. and Europe gotu kola is most often used to treat varicose veins and chronic venous insufficiency, a condition where blood pools in the legs. It's also used in ointments to treat psoriasis and help heal minor wounds.

Gotu kola is not the same as kola nut (Cola nitida). Unlike kola nut, gotu kola has no caffeine, and is not a stimulant.


Plant Description:

Gotu kola is a perennial plant native to India, Japan, China, Indonesia, South Africa, Sri Lanka, and the South Pacific. A member of the parsley family, it has no taste or smell. It thrives in and around water. It has small fan-shaped green leaves with white or light purple-to-pink flowers, and it bears small oval fruit. The leaves and stems of the gotu kola plant are used for medicinal purposes.


Medicinal Uses and Indications:

Treatment

Venous insufficiency and varicose veins

When blood vessels lose their elasticity, blood pools in the legs and fluid leaks out of the blood vessels. That causes the legs to swell (venous insufficiency). Several small studies suggest gotu kola may help reduce swelling and improve circulation. In a study of 94 people with venous insufficiency, those who took gotu kola saw their symptoms improve compared to those who took placebo. In another study of people with varicose veins, ultrasound tests showed improvements in the vascular tone -- meaning there was less leakage -- of those who took gotu kola.

Wound healing and skin lesions

Gotu kola contains chemicals called triterpenoids. In animal and lab studies, these compounds appear to help heal wounds. For example, some studies suggest that triterpenoids strengthen the skin, boost antioxidants in wounds, and increase blood supply to the area. Based on these findings, gotu kola has been applied to the skin, or topically, for minor burns, psoriasis, preventing scars after surgery, and preventing or reducing stretch marks.

You can find gotu kola in many topical preparations for wound healing. Ask your health care provider if one is right for you.

Anxiety

These same chemicals -- triterpenoids -- seem to decrease anxiety and increase mental function in mice. One human study found that people who took gotu kola were less likely to be startled by a new noise than those who took placebo. Since the "startle noise" response can be a way to tell if someone is anxious, researchers think that gotu kola might help reduce anxiety symptoms. But the dose used in this study was very high, so it's impossible to say how gotu kola might be used to treat anxiety.

Scleroderma

A single study of 13 women with scleroderma found that gotu kola decreased joint pain and skin hardening, and improved finger movement.

Insomnia

Gotu kola acts as a sedative when given to animals in tests. Because of that, it is sometimes suggested to help people with insomnia. But no human studies have been done to see whether it works and whether it's safe.


Dosage and Administration:

Gotu kola is available in teas and as dried herbs, tinctures, capsules, tablets, and ointments. Products should be stored in a cool, dry place and used before the expiration date on the label.

Pediatric

Gotu kola is not recommended for children under 18 years old.

Adult

The adult dosage of gotu kola varies depending on the condition being treated. Your health care provider can help you choose the right dose for you.

The standard dose of gotu kola (Centella asiatica) varies depending on the preparation. Most studies have used standardized extracts:
•Dried herb -- you can make a tea of the dried leaf, three times daily.
•Powdered herb, available in capsules -- 1,000 - 4,000 mg, three times a day
•Tincture (1:2 w/v, 30 % alcohol) 30 - 60 drops (equivalent to 1.5 - 3 mL -- there are 5 mL in a teaspoon), three times daily.
•Standardized extract -- 50 - 250 mg, two to three times daily. Standardized extracts should contain 40 % asiaticoside, 29 - 30 % asiatic acid, 29 - 30 % madecassic acid, and 1 - 2 % madecassoside. Doses used in studies mentioned in the Treatment section include 20 mg for scleroderma and up to 180 mg in one study for venous insufficiency, although most of the studies for this condition used 90 - 120 mg daily.


Precautions:

Gotu kola has been used in some studies that lasted up to one year. However, in some people gotu kola may affect the liver. It's best not to use gotu kola for more than 6 weeks without talking to your doctor. You may need to take a 2-week break before taking the herb again.

Asiaticoside, a major component of gotu kola, has also been associated with tumor growth in mice. Anyone with a history of precancerous or cancerous skin lesions -- such as squamous cell, basal cell skin cancer, or melanoma -- should not use gotu kola.

People with liver disease, or who take medications that affect the liver, should not take gotu kola.

Side Effects

Side effects are rare but may include skin allergy and burning sensations with external use, headache, stomach upset, nausea, dizziness, and extreme drowsiness. These side effects tend to happen with high doses of gotu kola.

Pediatric Use

Gotu kola is not recommended for children.

Geriatric Use

People older than 65 should take gotu kola at a lower than standard dose. Your health care provider can help you determine the right dose for you, which can be increased slowly over time.


Interactions and Depletions:

Gotu kola may interact with the following medications:

Drugs that affect the liver -- Gotu kola contains elements that may be harmful to the liver, and taking it along with some other medications that also can harm the liver may cause liver damage.

Cholesterol-lowering drugs (including statins) -- In animal studies, gotu kola increased cholesterol levels. It may also raise cholesterol levels in humans, although no studies have been done.

Diabetes medications -- In animal studies, gotu kola seems to increase blood sugar levels. People with diabetes should not take gotu kola without first talking to their doctor.

Diuretics (water pills) -- Gotu kola appears to have diuretic effects, meaning it helps the body get of excess fluid. Taking diuretic medications and gotu kola could cause your body to lose too much fluid, upsetting the balance of electrolytes you need. The same is true of taking gotu kola with herbs that have diuretic effects, such as green tea, astragalus, or gingko.

Sedatives -- Because of gotu kola's sedative effects, it might increase the effect of other medications taken to relieve anxiety or insomnia. It might also increase the effects of herbs taken for anxiety or insomnia, such as valerian.


Alternative Names:

Brahmi; Centella; Centella asiatica; Hydrocotyle; Indian pennywort; Luei gong gen; Marsh pennywort
•Reviewed last on: 10/11/2010
•Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.


Supporting Research

Antani JA, Kulkarni RD, Antani NJ. Effect of abana on ventricular function in ischemic heart disease. Jpn Heart J. Nov 1990: 829-835.

Anonymous. Centella asiatica (Gotu kola). Botanical Monograph. American Journal of Natural Medicine. 1996;3(6):22-26.

Ahshawat MS, Saraf S, Saraf S. Preparation and characterization of herbal creams for improvement of skin viscoelastic properties. Int J Cosmet Sci. 2008 Jun;30(3):183-93.

Belcaro GV, Rulo A, Grimaldi R. Capillary filtration and ankle edema in patients with venous hypertension treated with TTFCA. Angiology. 1990;41(1):12-18.

Biswas TK, Mukherjee B. Plant medicines of Indian origin for wound healing activity: a review. Int J Low Extrem Wounds. 2003;2(1):25-39.

Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J ClinPsychopharmacol. 2000;20(6):680-684.

Brinker F. Herb Contraindications and Drug Interactions. 3rd ed. Sandy, Or: Eclectic Medical Publication; 2001.

Brinkhaus B, Linder M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica. Phytomed. 2000;7(5):427-448.

Cauffield JS, Forbes HJM. Dietary supplements used in the treatment of depression, anxiety, and sleep disorders. Lippincotts Prim Care Pract. 1999:3(3):290-304.

DerMarderosian A, ed. Gotu Kola. In: Facts and Comparisons The Review of Natural Products. 5th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2008

Fetrow C, Avila J. Professional's Handbook of Complementary & Alternative Medicines. 2nd ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2001

Ivanov V, Ivanova S, Kalinovsky T, Niedzwiecki A, Rath M. Plant-derived micronutrients suppress monocyte adhesion to cultured human aortic endothelial cell layer by modulating its extracellular matrix composition. J Cardiovasc Pharmacol. 2008 Jul;52(1):55-65.

Jana U, Sur TK, Maity LN, Debnath PK, Bhattacharyya D. A clinical study on the management of generalized anxiety disorder with Centella asiatica. Nepal Med Coll J. 2010 Mar;12(1):8-11.

Kuhn M, Winston D. Herbal Therapy and Supplements: A Scientific and Traditional Approach. Philadelphia, Pa: Lippincott; 2001.

LaValle JB, Krinsky DL, Hawkins EB, et al. Natural Therapeutics Pocket Guide. Hudson, OH:LexiComp; 2000: 449-450.

Pittella F, Dutra RC, Junior DD, Lopes MT, Barbosa NR. Antioxidant and cytotoxic activities of Centella asiatica (L) Urb. Int J Mol Sci. 2009 Aug 26;10(9):3713-21.

Pointel JP, Boccalon H, Cloarec M, Ledevehat C, Joubert M. Titrated extract of centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiology 1987;38(1 Pt 1):46-50.

Shukla A, Rasik AM, Dhawan BN. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res. 1999;13(1):50-54.

Singh RH, Narsimhamurthy K, Singh G. Neuronutrient impact of Ayurvedic Rasayana therapy in brain aging. Biogerontology. 2008 Dec;9(6):369-74.

Subathra M, Shila S, Devi MA, Panneerselvam C. Emerging role of Centella asiatica in improving age-related neurological antioxidant status. Exp Gerontol. 2005;40(8-9):707-15.

Wollina U, Abdel-Nasar MB, Mani R. A review of the microcirculation in skin in patients with chronic venous insufficiency: the problem and the evidence available for therapeutic options. Int J Low Extrem Wounds. 2006;5(3):169-80.

Wojcikowski K, Wohlmuth H, Johnson DW, Rolfe M, Gobe G. An in vitro investigation of herbs traditionally used for kidney and urinary system disorders: Potential therapeutic and toxic effects. Nephrology (Carlton). 2008 Sep 22. [Epub ahead of print].
(QUOTE)
 
Üst Alt